Give girls big eyes or big anime eyes! At the time of posting this there's a few models on civit already, but I find they push towards an anime rendering style, so I trained this for a hint of realism.
In my generations, a weight of 0.7-1.7 with the term "big eyes" or "big anime eyes" works well, with upscaling at 1.0 weight. For extra fun, mix with "Waist Slider XL (Microwaist XL)" for some impossible anime proportions, or "Lori Aerly Big Eyes Style" for an exaggerated look.